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The charged drug leak hypothesis provides a potential explanation on how polymorphisms in pfcrt may directly mediate CQ resistance.

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22), so that the relationship between the fluorescence intensity and the mean occupancy number hni is I0 ln I 14hni ðB4:2:1Þ hni is related to the micellar aggregation number Nag by the following relation: hni 14 12Q 14 12QNag ðB4:2:2Þ where [Q] is the total concentration of quencher.

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(continued ) CHAPTER 17 17. Copyright 2015 Finance Magnates Ltd. This was apparently because of the absence of certain residues in the human framework binaary while not directly involved in antigen binding, are required to retain the CDR regions in the correct conformation.

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108(E12): 8096, 10. The dose of heparin may need to be reduced as the INR rises. IEEE Trans Med Imaging. n new Re1('str,eh.

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However, the result- ing Co-N distances are still too short, and the overall agreement for all five struc- tures considered is worse.

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